Fertility preservation before Hematopoietic Stem Cell Transplantation HSCT Treatment for Multiple Sclerosis (MS)

A really important issue for younger patients considering HSCT

Fertility preservation before hematopoietic stem cell transplantation (HSCT) is crucial for patients undergoing this treatment, as the chemotherapy an essential part 0f HSCT Treatment protocol often cause infertility

Why the need for Fertility preservation before Hematopoietic Stem Cell Transplantation HSCT Treatment

Conditioning agents like Cyclophosphamide used in HSCT treatment can lead to germline damage (oocytes and sperm). Therefore, fertile female patients should be advised about egg freezing prior to treatment, and male patients should be advised about sperm preservation. Several methods exist to preserve fertility, including oocyte and embryo cryopreservation, ovarian tissue cryopreservation, and sperm banking. The most appropriate method depends on the patient’s age, pubertal status, and the specific HSCT protocol.

Fertility Preservation Options

For Females :

Oocyte and Embryo Cryopreservation: This involves stimulating the ovaries to produce multiple eggs, which are then retrieved, fertilized (creating embryos), and frozen for future use. This is generally recommended for post-pubertal women.

Ovarian Tissue Cryopreservation (OTC): This involves surgically removing and freezing ovarian tissue, typically from the cortex, for later transplantation. This is a viable option for both pre-pubertal and post-pubertal girls and women.

Ovarian Suppression: Gonadotropin-releasing hormone (GnRH) agonists can be used to suppress ovarian function and potentially protect the ovaries from the damaging effects of chemotherapy.

For Males:

Sperm Banking: This involves collecting and freezing semen samples for future use in in vitro fertilization (IVF). Sperm cryopreservation is an established fertility preservation option for post-pubertal boys and men. Sperm can be used either for artificial insemination or, if the quantity and/or quality of sperm are insufficient, for intracytoplasmic sperm injections for in vitro fertilization

Testicular Tissue Cryopreservation: This is an experimental option for prepubertal males, involving freezing testicular tissue with the aim of future spermatogonial stem cell transplantation or testicular tissue grafting.

Important Considerations : Fertility Preservation before HSCT treatment for Multiple Sclerosis for younger patients.

1. Timeliness:

Fertility preservation should be addressed before the start of HSCT treatment, ideally during the initial consultation with a hematologist or oncologist.

4. Cost and Accessibility:

The cost of fertility preservation and insurance coverage are add ons to already expensive HSCT cost. So the patients should be aware and prepared for these.

5. Safety:

Fertility preservation procedures are generally considered safe, but potential risks even though small must be discussed.

Fertility preservation before HSCT is an essential aspect of comprehensive care for MS patients and aims to preserve their future reproductive potential.

Importance of considering a large Multidisciplinary Hospital Facility for HSCT

HSCT Hospitals in India are world class facilities Accredited by Joint Commission, USA. Our team of globally renowned medical professionals with rich experience of working at world’s leading hospitals and adherence to patient-centric processes have enabled it to set new benchmarks for patient service and care in this part of the world. Fertility preservation procedures are done with great precision and quality care by a multidisciplinary team

To know more about HSCT Hospital India please Click here

HSCT (Hematopoietic Stem Cell Transplantation) for Multiple Sclerosis is now available at JCI-USA accredited World Class Hospital in India at most affordable cost.

HSCT attempts to “reboot” the faulty immune system, which is responsible for damaging the brain and spinal cord in MS. At present the total cost of HSCT at major centres like Mexico and Russia cost more than 100,000 US Dollars including travel and stay. At world class HSCT Hospital India HSCT costs about 30,000 US Dollars all inclusive. Please click this link to know more about world’s most affordable HSCT treatment Please click this link to know more about world’s most affordable HSCT treatment

Why you should choose HSCT Hospital India for HSCT ?

• HSCT Hospital India is one of the finest private hospitals in India and Accredited by JCIUSA. Most Affordable, 30,000 US $ HSCT package includes complete treatment cost for 30 days inhospital stay in a deluxe private room, Doctors Fee, Tests and Consultations, Medicines, Consumables, Neuro-Physiotherapy and also Food and Laundry for both the patient and the attendant, Airport Transfers etc. Large number of MS patients from Europe, America and Australia already treated successfully. Click here to know more
• Complete 30 day HSCT done in hospital. Private deluxe rooms are very well served for patient and attendant’s comfort and equipped with HEPA Filter with Triple Level Air Filtration. No outside hospital stay avoids risk of infection, 24 x 7 nursing care and best medical attention. Advanced HSCT for MS protocol used does not require any further chemo/ treatment after leaving the hospital. Click here to get complete details
• International and Globally Renowned Accreditations – HSCT Hospital India is accredited by the Joint Commission International, USA, National Accreditation Board for Hospitals and Healthcare Providers (NABH), and National Accreditation Board for Laboratories (NABL) for processes and high-quality patient care.
• Large number of MS patients from Europe, America and Australia have already been treated successfully at HSCT Hospital India. Click here to watch patient testimonial videos